PTPRA (protein tyrosine phosphatase, receptor type, A)

PTPRA ( protein tyrosine phosphatase , receptor type , A )

Review on PTPRA, with data on DNA/RNA expression, on the protein encoded, and the functional importance of the gene.

UCSD MOLECULE PAGES Tyrosine-protein phosphatase non-receptor type 2

TC-PTP is a ubiquitous non-receptor type protein tyrosine phosphatase that shows highest expression in hematopoietic tissues. It regulates many signal transduction pathways in hematopoietic as well as non-hematopoietic cells. TCPTP has two splice variants, an endoplasmic reticulum-localized TC48, and predominantly nuclear TC45. Upon various stress conditions and insulin stimuli, TC45 comes out ...

PTPN 1 ( protein tyrosine phosphatase , non - receptor type 1 )

Protein Tyrosine Phosphatase Receptor Type g Is a JAK Phosphatase and Negatively Regulates Leukocyte Integrin Activation

Protein tyrosine phosphatase receptor type γ is a JAK phosphatase and negatively regulates leukocyte integrin activation.

Regulation of signal transduction networks depends on protein kinase and phosphatase activities. Protein tyrosine kinases of the JAK family have been shown to regulate integrin affinity modulation by chemokines and mediated homing to secondary lymphoid organs of human T lymphocytes. However, the role of protein tyrosine phosphatases in leukocyte recruitment is still elusive. In this study, we a...